PICO is an acronym describing a format that you can use to develop a clinical research question. By identifying terms related to each of the four PICO elements, you will be able to perform more precise database searches.
P - Patient population (May be an individual or group)
I - Intervention (The treatment being considered)
C - Comparison (The absence of the treatment, alternative treatment, or control group)
O - Outcome (The result being sought)
(T) - In some cases, the time frame needed to reach the desired outcome is included.